New information on
the use of AZILECT(R) (rasagiline tablets) for the treatment of Parkinson's
disease (PD) was reported this week at The Movement Disorder Society's
congress in Istanbul, Turkey. Once-daily AZILECT was approved by the FDA
May 17, 2006, for the treatment of the signs and symptoms of PD, both as
initial monotherapy and as adjunct therapy to levodopa.
AZILECT(R) Monotherapy Demonstrates Benefits in Early PD Regardless of
Disease Duration
Dr. John Bertoni, M.D., Ph.D., Creighton University provided the
results of a new post-hoc analysis of the 26-week, multicenter, randomized,
double-blind TEMPO study, that included 404 patients who received
once-daily AZILECT 1mg, 2mg, or placebo. This analysis revealed that
AZILECT once-daily as monotherapy provided a consistent beneficial effect
on the symptoms of PD regardless of the duration of the disease at the time
treatment was started. AZILECT 1 mg/day significantly improved UPDRS-Total
score compared to placebo in both the < 1-year stratum (-0.52 vs 3.33;
p